What Are Bioidentical Hormones?
Friday 10/22/2021

Bioidentical hormones are the safest and most natural form of hormone replacement available.

Bioidentical hormones are the safest and most natural form of hormone replacement available because they are created using familiar, plant-based ingredients like yams, soy, or olive oil. The Mayo Clinic has defined bioidentical hormones as “compounds that have the same chemical and molecular structure as hormones that are produced in the human body.” That means the body recognizes bioidentical hormones as its own, which is critical. Conventional hormone replacement therapy uses drugs that are dangerous chemical compounds, and their structure is likely to have adverse consequences on the human organism.

Hormones are not drugs. Hormones are regulatory substances created in the endocrine glands and transported in the blood to stimulate specific tissues into action. They are made up of signaling molecules that target organs to regulate physiology and behavior. Bioidenticals do not come with the undesirable side effects of traditional hormone drugs because they are identical, chemically speaking, to those made by your own body.

Bioidentical hormones are infinitely safer because they are the structural duplicates to the hormones your body produced a lot of when you were young. Hence, the term bioidentical as in identical to your biology.

The Optimal Bio Pellet

The pellets we use at Optimal Bio are made up of 99.5% natural testosterone that comes from yams. Their chemical structure is molecularly identical to the testosterone made in your own body. The other 0.5% of the pellet is composed of stearic acid which allows the testosterone to hold together and to dissolve slowly after placement. This identical-ness is the primary differentiator between bioidentical and synthetic hormones. Your body will not reject or react against bioidenticals. Unlike synthetic hormones that have dangerous side effects, BHRT is safe and effective.

The History of Pellets

Researchers in the early 1930s first isolated the testosterone hormone. The first scholarly paper published on testosterone pellet therapy was in a British Journal in 1935. Pellet therapy was then approved for medical use in 1939.That’s nearly eighty years ago! BHRT is not something new. It has been around a long time, and its safety has been proven for far longer than most of the prescription drugs so many Americans take.

Why We Use Pellets

There are several different methods of delivery for bioidentical hormones, including creams, gels, troches (small lozenges that dissolve between the cheek and gum), pills, injections, and pellets. All are better than taking synthetic hormones! However, the best and most effective method of bioidentical hormone delivery is the insertion of pellets, and that is why we use pellets exclusively at Optimal Bio.

Bioidentical pellet treatments mimic your ovary and testicle production identically. When a topical cream is used, the testosterone is not absorbed as readily through the skin, and the results are limited. Similarly, when pills are taken orally, not enough of the hormone is absorbed through the digestive tract. Treatment through intravenous injections is outlawed for women. They are available for men only, and even with that method, testosterone injections result in levels that mimic a roller coaster, with up-and-down surges of high and low hormone levels.

Pellet therapy is the only method of treatment that allows your hormone levels to remain constant for months at a time, precisely the way your body does naturally, producing a steady supply of hormones that flows directly into the bloodstream. As you work out, your blood flow increases, and more testosterone flows through your system, just as it was designed to do. Pellet therapy is ideal because it provides a steady supply of life-giving hormones. The pellets also act as a reservoir. When the heart rate increases, more testosterone is transported into the bloodstream.

Since the pellet dissolves over time, you will want to get additional ones placed again after about four months. Why so soon if the pellet is designed to last up to six months? Because you never want to go too low again. Getting placed again after four months will prevent you from bottoming out, sending your body into a downward spiral of feeling lethargic, mentally unfocused, and devoid of a healthy libido.

The Benefits of Our Pellet Therapy

Take a moment and read through the benefits of BHRT listed below. Does this sound like the positive health model you have been seeking?

The Benefits of Bioidentical Hormones

Absorbed directly into the blood

Lowers your chance of diabetes

Lowers cholesterol 

Reduces your chance of obesity

Improves clarity

Improves cognitive ability

Lowers your risk of Alzheimer’s

Increases lean muscle mass

Lowers your risk of depression

Reduces your risk of cancer

Increases your energy level

Creates a strong sex drive

Lowers your risk of heart attacks

Lowers your risk for blood clots

Lowers your risk of a stroke

Reduces your risk of dementia

Increases bone density

The dangers of bioidentical hormones are so minimal that I would venture to say it is more dangerous not to be on them. That is the degree of protection they offer against various ailments as we get older. There are, of course, a few minor side effects. They are, however genuinely insignificant in comparison to the extraordinary benefits of BHRT.

It is the conclusion of doctors and researchers all around the world that bioidentical hormone replacement therapy is safe, proven, and effective.


I have read extensively about the safety of BHRT, and I have never seen any research that revealed any significant health risks. The research shows there are no significant dangers associated with this treatment.


Through our website, you will have access to thousands of scientific articles that outline the proven results of BHRT.


I’ve seen the phenomenal changes in thousands of lives at Optimal Bio in the last seven years.

Safe, proven, and effective are the words I would use to describe bioidentical hormones. If you aren’t feeling quite like yourself, we’re here to help. Contact our office today or visit us at one of our five office locations: Cary, Southern Pines, Wilmington, Charlotte, and Charlottesville. 


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